The actor is opening up about how the costars’ personal battles ultimately strengthened their bond.

John Stamos recalls how tragedies helped him and Bob Saget overcome their early tension on Full House

The actor is opening up about how the costars’ personal battles ultimately strengthened their bond.

By Leigh Blickley

July 9, 2026 1:57 p.m. ET

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(L) Bob Saget and John Stamos. Credit: Stephen Lovekin/Getty Images

- John Stamos is opening up about how personal tragedies helped him and the late Bob Saget bond on *Full House*.

- Stamos spoke to Bobby Bones about his and Saget’s early tension on set before becoming friends.

- Stamos said Saget’s death was “a tragic loss.”

John Stamos is opening up about his late friend Bob Saget and how they developed their tight-knit bond on *Full House*.

During a recent appearance on Bobby Bones’ *BobbyCast* podcast, Stamos admitted he and Saget didn’t initially get along when they were cast as brothers-in-law Jesse Katsopolis and Danny Tanner on *Full House* in 1987.

Stamos didn’t like how, as stand-up comedians, Saget and their costar Dave Coulier only seemed to care about making the crew laugh.

“I was coming from, I just did a show with Jack Klugman, who’s a famous sitcom guy, and so I was coming to [*Full House*] with more of an actor’s point of view of these scenes and trying to work these scenes,” Stamos told Bones. “And the guys were just trying to make the guys, the crew, laugh and whatever that was about.”

John Stamos, Bob Saget, and Dave Coulier on ‘Full House’.

Stamos noted that Saget was “especially” distracting on set. But when tragedy struck all their families, the trio learned that they had more in common than they originally thought.

“We didn’t get along at all for the first couple of years,” Stamos explained. “And then I think it was maybe the third or fourth, something like that, season [and] Bob’s sister got scleroderma —which he spent the rest of his life advocating raising money for this horrific disease —Dave’s sister got cancer, and my sister had gotten diagnosed with a brain tumor. And so all of a sudden we weren’t three guys on a show, we were three brothers grieving, you know, our sisters.”

Sadly, Saget and Coulier lost their sisters, while Stamos’ sibling survived. Their shared heartbreak turned into a lasting brotherhood.

“We became really close then, and then we just started to, you know, realized that there was a lot to learn from each other, I think, and I had a lot to learn. I learned a lot from those guys,” Stamos insisted.

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He added that Saget, who died in 2022 after a fall, became his best friend.

“We were just there for each other through every, you know, all the ups and downs of life, divorces, marriages,” Stamos said. “But I just loved him so dearly, and it was such a tragic loss. Just one day, just in a blink of an eye, he was gone.”

He noted that Saget was “bombastic with his love” and would text him constantly and then call to make sure he received the texts. He misses those messages.

“He was that kind of guy,” Stamos told Bones. “Just losing him has been a real, you know, life has just been a little not as funny.”

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Coulier has faced his own health battle after being diagnosed with stage 3 non-Hodgkin lymphoma in 2024 and p16 squamous carcinoma (a head-and-neck cancer at the base of his tongue) in 2025. He is now in remission.

“Dave and I talk a lot,” Stamos told *Us Weekly* last year. “You know, we lost Bob, and I couldn’t bear losing Dave, so I’ve been with him a lot during this cancer journey of his.”

He added of Coulier, who played Danny’s best friend Joey Gladstone on *Full House*, “It’s great to see that the treatments work. And it’s great to see him out there talking about it, to help other people that are going through the same thing.”

Listen to Stamos on *The Bobbycast* above.

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